Targeting Brain Inflammation For Improved Functional Recovery in Acute Neurodegenerative Disorders

The TargetBraIn is European Large-scale Integrating Project Consortium of 7 academic groups and 2 companies funded by EU within 7th Framework Program (FP7).

This consortium was awarded a EU grant to directly address the topic “Understanding the role of neuroinflammation in neurodegenerative diseases” and was launched on December 1, 2011.

The work carried out by TargetBraIn aims to understand the cross-talk between neural stem cells and immune cells as a possible key to better brain repair after stroke. It should lead to development of immune-based therapeutic protocol to promote functional recovery in stroke patients based on enhancement of cellular plasticity.

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  • Last updated 21 March 2016.


TargetBraIn News and Events

13th International Congress of Neuroimmunology, Jerusalem | 26-29 September 2016.


TargetBraIn Publications

Poststroke angiogenesis, con: dark side of angiogenesis. Adamczak, J., and Hoehn, M. (2015) Stroke 46, e103-104.

Novel bimodal iron oxide particles for efficient tracking of human neural stem cells in vivo. Aswendt, M., Henn, N., Michalk, S., Schneider, G., Steiner, M.S., Bissa, U., Dose, C., and Hoehn, M. (2015). Nanomedicine (Lond) 10, 2499-2512.

PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease. Baruch, K., Deczkowska, A., Rosenzweig, N., Tsitsou-Kampeli, A., Sharif, A.M., Matcovitch-Natan, O., Kertser, A., David, E., Amit, I., and Schwartz, M. (2016). Nat Med. 2016, 22:135-7.


Scientific news

Stimulating brain with electricity 'boosts stroke recovery'

Stimulating the brain with electrical current can help boost recovery after a stroke, research from the University of Oxford suggests. The team found patients who were given electrical stimulation...